Clinical Manual for Management of the HIV-Infected Adult
2006 Edition

Section 10: Resources

Antiretroviral Reference Tables

Drug Characteristics

• Characteristics of Nucleoside Reverse Transcriptase Inhibitors (NRTIs) (DHHS: Table 11)
• Characteristics of Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) (DHHS: Table 12)
• Characteristics of Protease Inhibitors (PIs) (DHHS: Table 13)
• Characteristics of Fusion Inhibitors (DHHS: Table 14)

Regimen Selection

• Antiretroviral Regimens Recommended for Treatment of HIV-1 Infection in Antiretroviral-Naive Patients (DHHS: Table 6)
• Advantages and Disadvantages of Antiretroviral Components Recommended as Initial Antiretroviral Therapy (DHHS: Table 7)
• Options for Once-Daily Dosing of Antiretrovirals (NRC: Coffey)

Drug Interactions

• Dosage Adjustments for ARV-ARV Drug Interactions (NRC: Coffey, McNicholl)
• Drugs That Should Not Be Used With PI or NNRTI Antiretrovirals (DHHS: Table 20)
• Drug Interactions Among Antiretrovirals and Other Drugs) (DHHS: Table 21)

Adverse Effects

• Adverse Events of Antiretroviral Drugs (NRC: Coffey, McNicholl)
• Potentially Life-Threatening and Serious Adverse Events (DHHS: Table 17a)
• Adverse Events With Potential Long-Term Complications
• Adverse Effects Compromising Quality of Life and/or With Potential Impact on Medication Adherence (DHHS: Table 17c)

Special Situations

• Preclinical and Clinical Data Relevant to the Use of Antiretrovirals During Pregnancy (DHHS: Table 28)
• Dosing for Ritonavir-Boosted Protease Inhibitors (NRC: Coffey, McNicholl)
• Dosing of Antiretroviral Drugs in Adults with Renal Insufficiency and Hemodialysis (NRC: McNicholl, Rodriguez)

Table Sources

• DHHS = U.S. Department of Health and Human Services. Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents. May 4, 2006. Available online at aidsinfo.nih.gov/Guidelines/GuidelineDetail.aspx?GuidelineID=7.
• NRC = AETC National Resource Center, Antiretroviral Reference Tables for Clinicians, April 2006. Available online at aidsetc.org/aidsetc?page=et-03-01.