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Antiretroviral Treatment of Adult HIV Infection: 2010 Recommendations of the International AIDS Society-USA Panel

Date: 07/21/2010
Source: International AIDS Society-USA
Authors: Melanie A. Thompson, MD; Judith A. Aberg, MD; Pedro Cahn, MD; Julio S.G. Montaner, MD; Giuliano Rizzardini, MD; Amalio Telenti, MD, PhD; José M. Gatell, MD, PhD; Huldrych F. Günthard, MD; Scott M Hammer, MD; Martin S. Hirsch, MD; Donna Jacobsen, BS; Peter Reiss, MD, PhD; Douglas D. Richman, MD; Paul A. Volberding, MD; Patrick G. Yeni, MD and Robert T. Schooley, MD

Antiretroviral Treatment of Adult HIV Infection: 2010 Recommendations of the International AIDS Society-USA Panel

Description:

JAMA. 2010;304(3):321-333.

From the abstract conclusion: "Patient readiness for treatment should be confirmed before initiation of antiretroviral treatment. Therapy is recommended for asymptomatic patients with a CD4 cell count ≤500/µL, for all symptomatic patients, and those with specific conditions and comorbidities. Therapy should be considered for asymptomatic patients with CD4 cell count >500/µL. Components of the initial and subsequent regimens must be individualized, particularly in the context of concurrent conditions. Patients receiving antiretroviral treatment should be monitored regularly; treatment failure should be detected and managed early, with the goal of therapy, even in heavily pretreated patients, being HIV-1 RNA suppression below commercially available assay quantification limits."

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Topic Areas:

Antiretroviral Therapy, Starting Treatment

Resource Type:

Antiretroviral Guidelines

Group:

Guidelines

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