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HIV Meds Quarterly

Source: AETC National Resource Center and UCSF Center for HIV Information

Description: HIV Meds Quarterly provides brief updates and analysis of new findings related to common therapies used by HIV clinicians.

Spring/Summer 2010

dotInteractions: Rosuvastatin Levels Increased by Ritonavir-Boosted Darunavir; Fosamprenavir and Posaconazole
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dotResearch Briefs: Recent Advances in Once-Daily Therapies and Fixed-Dose Combination Regimens: Rilpivirine (TMC278) in Initial Therapy; S/GSK 572 in Initial Therapy: Interim Results of SPRING-1; Efficacy and Safety of Elvitegravir/Cobicistat/Emtricitabine/Tenofovir ("Quad" Pill) in Initial Therapy; Novel Pharmacokinetic Booster Cobicistat (GS-9350)
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dotFast Takes: Maraviroc in patients with kidney disease; Didanosine and noncirrhotic portal hypertension
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dotReference Table: Updates to the Database of ARV Drug Interactions
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Winter 2010

dotInteractions: Efavirenz and Levonorgestrel; Lopinavir/ritonavir and Buprenorphine
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dotResearch Brief: Vicriviroc in Treatment-Experienced Patients
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dotFast Takes: Ritonavir tablet formulation; Maraviroc approved for initial therapy; Saquinavir/ritonavir and possible risk of abnormal heart rhythms
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dotReference Table: Updates to the Database of ARV Drug Interactions
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Fall 2009

dotResearch Briefs: Kaletra Dosage Adjustment for Patients on Efavirenz or Nevirapine; Once-Daily Raltegravir; Atazanavir and Lopinavir/Ritonavir in Hemodialysis
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dotReference Table: Updates to the Database of ARV Drug Interactions
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Summer 2009

dotResearch Briefs: Regimen Simplification: Atazanavir vs Atazanavir/Ritonavir; Atazanavir/Ritonavir in Pregnancy; Investigational Integrase Inhibitor Shows Potent Activity in Early Studies
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dotReference Table: Updates to the Database of ARV Drug Interactions
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dotFast Takes: Raltegravir approved for initial therapy
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Spring 2009

dotResearch Briefs: Rosiglitazone and Heart Disease; Antipsychotics and Sudden Cardiac Death; New Pharmacokinetic Booster on the Horizon; Interleukin-2: No Clinical Benefit; Raltegravir Substitution for Lopinavir/Ritonavir (SWITCHMRK Study); Abacavir and Myocardial Infarction Risk: Additional Data
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dotReference Table: Updates to the Database of ARV Drug Interactions
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dotFast Takes: Darunavir: Traditional approval
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dotGuidelines: New Guidelines: Adult OI prevention and treatment; Updated: Pediatric ARV guidelines; Updated: Perinatal guidelines
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Winter 2009

dotResearch Briefs: Darunavir Approved for Use with Boosted Ritonavir as "Preferred" PI, Pediatric Dosing
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dotFast Takes: Recent news about maraviroc, abacavir: pediatric formulation, and abacavir/lamivudine: DHHS recommendations
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Fall 2008

dotResearch Briefs: Pregabalin for Neuropathic Pain: Not More Effective Than Placebo; Abacavir/Lamivudine: Higher Rates of Virologic Failure in ARV-Naive Patients with HIV RNA ≥100,000 copies/mL compared with Tenofovir/Emtricitabine; Abacavir and Risk of Myocardial Infarction: The SMART Study
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dotInteractions: Atazanavir: Interactions with Efavirenz, Nevirapine, and Oral Hormonal Contraceptives
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dotFast Takes: Recent news about ritonavir, darunavir, atazanavir + ritonavir, tenofovir, zidovudine, and didanosine
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Summer 2008

dotResearch Briefs: Abacavir and Didanosine Associated with Increased Risk of Myocardial Infarction; Testing for Chemokine Coreceptor Tropism
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dotInteractions: Rosuvastatin with Lopinavir/Ritonavir and Tipranavir; Rifampin and "Super-Boosted" Protease Inhibitors
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dotFast Takes: Recent news about nelfinavir, tipranavir, lopinavir/ritonavir, and nevirapine
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Spring 2008

dotResearch Briefs: Atazanavir Efficacy Data and Changes in Dosage Recommendations; Raltegravir Substitution for Enfuvirtide; HLA-B*5701 Screening
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dotReference Table: Etravirine-ARV Interactions
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dotFast Takes: Recent news about darunavir, lamivudine, lopinavir/ritonavir and amprenavir
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