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participating institutions:
Johns Hopkins University AIDS Service, New York State DOH AIDS Institute, The CORE Center, Cook County Hospital



POST-EXPOSURE PROPHYLAXIS

last updated: June 29, 2001


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Updated U.S. Public Health Service Guidelines for the Management of Occupational Exposures to HBV, HCV, and HIV and Recommendations for Postexposure Prophylaxis

Reprinted from the MMWR June 29, 2001/ 50(RR-11);1-42

The MMWR series of publications is published by the Epidemiology Program Office, Centers for Disease Control and Prevention (CDC), U.S. Department of Health and Human Services, Atlanta, GA 30333.

Summary
Introduction
   Definition of Health-Care Personnel and Exposure
Background
   Occupational Transmission of HBV

   Occupational Transmission of HCV
   Occupational Transmission of HIV
Recommendations for the Management of HCP Potentially Exposed to HBV, HCV, or HIV

   Hepatitis B Vaccination
   Treatment of an Exposure Site
   Exposure Report
   Evaluation of the Exposure and the Exposure Source
   Management of Exposures to HBV
   Management of Exposures to HCV
   Management of Exposures to HIV
   Recommendations for the Selection of Drugs for HIV PEP
   Occupational Exposure Management Resources
References
Appendices

Table 1. Reported instances of failure of combination drug postexposure prophylaxis to prevent HIV infection in health-care personnel exposed to HIV-infected blood
Table 2. Primary side effects associated with antiretroviral agents
Table 3. Recommended postexposure prophylaxis for exposure to hepatitis B virus
Table 4. Recommended HIV postexposure prophylaxis for percutaneous injuries
Table 5. Recommended HIV postexposure prophylaxis for mucous membrane exposures and nonintact skin* exposures




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