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hrsa

participating institutions:
Johns Hopkins University AIDS Service, New York State DOH AIDS Institute, The CORE Center, Cook County Hospital



ART & PREGNANCY

last updated: May 4, 2001


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TABLE 5. Rate of perinatal transmission according to receipt of zidovudine during pregnancy and mode of delivery
Transmission Rate
Study design (reference)
Therapy
Elective CS
Other modes
Odds ratio (95% Cl)
Observational data (128)
No ZDV
58/559 (10.4%)
1021/5385 (19%)
0.49 (0.4-0.7)
ZDV
4/196 (2%)
92/1255 (7.3%)
0.26 (0.07-0.7)
Randomized trial (129)
No ZDV
2/51 (4%)
16/82 (20%)
0.20 (0-0.8)
ZDV
1/119 (1%)
5/117 (4%)
0.20 (0- 1.7)




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