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participating institutions:
Johns Hopkins University AIDS Service, New York State DOH AIDS Institute, The CORE Center, Cook County Hospital



NEWS AND NEW DEVELOPMENTS



Ischemic Cardiovascular Disease in Persons with Human Immunodeficiency Virus Infection [David MH et al. CID 2002:34:98] The authors reviewed the records of 951 persons with HIV infection seen at the University of Cincinnati Infectious Disease Clinic to identify patients with proven ischemic cardiovascular disease. There were 16 patients (1.7%) who were compared with 32 controls selected by age and sex. The results showed that patients with CVD had significantly more recognized risk factors for this complication, lower CD4 cell counts, and longer prior exposure to nucleosides, but no clear association with exposure to protease inhibitors. The authors conclude that CVD in these patients was primarily associated with traditional risk factors such as hypertension and elevated cholesterol.
Comment: The main concern with this and many similar studies is the duration of follow-up and sample size.
posted 1/18/2002





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