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FDA
and Bristol Myers Squibb Warn Against the Use of Zerit in Combination
with Videx in HIV-Infected Pregnant Patients due to Potential Increased
Risk of Lactic Acidosis [FDA talk paper T01-02, 1/5/01]: On
January 5, 2001, BMS sent a letter alerting health care professionals
concerning the increased risk of lactic acidosis and hepatic steatosis
in pregnant women treated with d4T and ddI. The report is based
on three cases of fatal lactic acidosis that occurred in pregnant
women treated with this combination. The concern with use in pregnancy
will now appear as a black box warning.
posted
1/26/2001

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