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Experts
debate broad drug prophylaxis policy for HIV infected in Africa
[Stencel C. ASM News 2001;67:131]: TMP-SMX
costs $8-$17/person/year, has established merit including two favorable
studies done in Cote d'Ivoire and is supported by the CDC, Doctors
Without Borders, and UNAIDS. Nevertheless, concern is expressed
that it may not work as well in all areas of Africa and there is
the problem of escalating antibiotic resistance to TMP-SMX by Salmonella
and S. pneumoniae. WHO and UNAIDS have finalized their policy
statement recommending cotrimoxazole be made available for daily
use among HIV-infected persons throughout Africa. Nevertheless,
the issue is still debated.
posted
3/20/2001

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