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Resistance
study to re-evaluate HAART [Kenyon
G. Nat Medicine 2001; 7: 515]:This report announces the anticipated
launch of Optima in June 2001. This is a $15.3 million study entitled
"Options in Management with Antiretrovirals Study" and will be the
first study done by the Tri-National Clinical Trials Research Institute
which represents a collaboration between the Canadian Institutes
of Health Research, the VA in the United States, and the Medical
Research Council in the United Kingdom. Over 3 years, the trial
will include an estimated 1,700 patients at 70 sites, including
22 hospitals in Canada, 25 in the U.K. and 30 VA hospitals in the
U.S. The initial study will examine relative benefit of five versus
three antiretroviral agents after STI with the choice of agents
left to physician decision.
posted
6/20/2001
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