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participating institutions:
Johns Hopkins University AIDS Service, New York State DOH AIDS Institute, The CORE Center, Cook County Hospital



NEWS AND NEW DEVELOPMENTS



Long-Term Efficacy on Kaposi's Sarcoma of Highly Active Antiretroviral Therapy in a Cohort of HIV-Positive Patients [Dupont C, et al. AIDS 2000; 14: 987]: This is a prospective study from France that addresses the issue of the impact of HAART on Kaposi's sarcoma. There were 39 AIDS patients with KS who began therapy with HAART during 1996. At month 24, the KS response was complete in 46% and partial in an additional 28%. The strongest predictor of response was the CD4 cell count increase; the viral load response was not significantly associated as an independent variable.
Comment: KS appears to be another chronic opportunistic infection in which immune reconstitution is an important component of treatment. posted 7/19/2000







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