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participating institutions:
Johns Hopkins University AIDS Service, New York State DOH AIDS Institute, The CORE Center, Cook County Hospital



NEWS AND NEW DEVELOPMENTS



Relation of Lean Body Mass to Health-Related Quality of Life in Persons with HIV [Wilson IB, et al. JAIDS 2000; 24: 137]: This study from the New England Medical Center for Nutrition is based on a cross-sectional analysis of 619 patients with HIV infection. Lean body mass (LBM) was tested by bioimpedance, and questionnaires were used to determine physical functioning, general health perception, energy, and days in bed in the past month. The mean CD4 cell count was 352/mm3. The results in men showed that a 10 kg increase in LBM was associated with a 3.7 point increase in physical functioning on a 0 - 100 scale and a 4.8 point increase in general health perceptions. The authors concluded that LBM was significantly related to physical functioning and other measures of quality of life in men, but the relationship was weak, and there was no clear association in women.
Comment: This study has potential importance in interventions, sometimes very expensive interventions, designed to increase LBM. posted 8/29/2000







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