Cell-Free Virus in Breast Milk of HIV-1-Seropositive Women
[Pillay K, et al. JAIDS 2000;24:330]: The authors studied
levels of HIV RNA in breast milk of pregnant women in Durban, South
Africa. Virus was detected in 86 of 136 samples (63%) from 79 participants.
There was a positive correlation with plasma HIV levels and with
risk of perinatal transmission. Comment: It is estimated that breast feeding may account
for up to 50% of perinatal transmissions of HIV in developing countries
[Lancet 1992;340:585]. This study shows the expected: Levels
of HIV in breast milk generally reflected plasma levels, and the
risk of transmission correlated with virus concentrations. posted
10/6/2000